| ncRNA name | hsa-let-7 |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples |
| Methods | immunohistochemistry, semi-qRT-PCR |
| Expression pattern | down-regulated |
| Functional description | Our findings imply that the overexpressions of high-mobility group A1, high-mobility group A2, and down-regulation of let-7 may be associated with tumorigenesis and progression of retinoblastomas. |
| PubMed ID | 20004941 |
| Year | 2010 |
| Title | Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. |
| Drug-related ncRNA | NO |
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